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How many units / retatrutide / not FDA-approved

How Many Units Is 4 mg of Retatrutide?

4 mg is a dose used in clinical trials of retatrutide. To show it in units on a U-100 insulin syringe, divide 4 mg by a made-up strength in mg per mL, then multiply by 100. At a made-up 5 mg/mL it’s 80 units. At 10 mg/mL it’s 40 units, and at 20 mg/mL it’s 20 units. These numbers are only math examples. Retatrutide is still being studied and has no approved vial strength or brand-name product. In the published TRIUMPH trials, study groups reach 4 mg by stepping up the dose as part of the research, not on an approved schedule. A number with no approved product label behind it doesn’t show that a product is available, sterile (germ-free) or effective, or that its strength is right.

Last updated

How U-100 syringe math works, using doses from clinical trials as the example. Whether a dose can be read exactly depends on the lines printed on the U-100 insulin syringe.
Strength (mg per mL)LiquidUnits on a U-100 insulin syringeOn a 1 mL syringe
5 mg/mL0.8 mL80right on a line
10 mg/mL0.4 mL40right on a line
20 mg/mL0.2 mL20right on a line

A U-40 or other syringe would give a different draw for this 4 mg Retatrutide example.

This page answers the 4 mg Retatrutide example; use the strength printed on your label.

Still being studied: Retatrutide is not FDA-approved. We're not saying it's available or that anyone should use it.

Your numbers

If the label gives a total mg and a total mL instead, divide the mg by the mL.

Syringe size and line spacing

The syringe's barrel or packaging says 0.3 mL, 0.5 mL or 1 mL (or 30, 50 or 100 units).

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Where 4 mg fits in the trials

In the published TRIUMPH trial plans, study groups go from 2 mg to 4 mg after 4 weeks. The 4 mg group is a trial step after 2 mg. This is background from trials of a medicine still being studied, never personal dosing advice.

Brand-name products

No brand-name product gives this amount. For retatrutide, that’s expected. It is still being studied, is not FDA-approved, and has no approved product.

Questions about 4 mg

Is 4 mg an approved retatrutide dose?

No. This page uses 4 mg, a dose from published clinical trials, only as an example for U-100 insulin syringe math. It is not part of any approved schedule.

How many units is 4 mg at the example strength?

At 20 mg/mL, 4 mg is 20 units on a U-100 insulin syringe. Whether that can be read exactly depends on the lines printed on the syringe.

Related guides

The basics behind this answer, then the calculator for your own vial.

  1. 01Units vs mL vs mg
  2. 02How to read an insulin syringe
  3. 03Insulin syringe sizes
  4. 04Common dosing mistakes
  5. 05The retatrutide calculator

Sources

The medical and device facts on this page come from these sources. Each entry shows the date we accessed it.

  1. 01 Retatrutide in the TRIUMPH-1 obesity trial · Eli Lilly and Company, 05/21/2026. Accessed 2026-09-28.
  2. 02 Retatrutide in the TRIUMPH-2 and TRIUMPH-3 trials · Eli Lilly and Company, 07/23/2026. Accessed 2026-09-28.
  3. 03 Retatrutide in the TRIUMPH-4 knee osteoarthritis trial · Eli Lilly and Company, 12/11/2025. Accessed 2026-09-28.
  4. 04 FDA's concerns with unapproved GLP-1 drugs used for weight loss · U.S. Food and Drug Administration, 10/01/2026. Accessed 2026-10-01.
  5. 05 Technical Data Sheet – Insulin Syringes · embecta, Rev B, 12/2025. Accessed 2026-09-28.
  6. 06 Injection technique guide · embecta, ©2025, EMB-05148. Accessed 2026-09-28.
  7. 07 Getting Started booklet · embecta, ©2023. Accessed 2026-09-28.
  8. 08 SafetyGlide Insulin Syringes quick reference guide · embecta. Accessed 2026-09-28.
  9. 09 ISO 8537:2016, sterile single-use insulin syringes · International Organization for Standardization, 2016. Accessed 2026-09-28.

Medically reviewed by Ashley Alexis, NDLast reviewed How we review